Article

A factorial Mendelian randomization study to systematically prioritize genetic targets for the treatment of cardiovascular disease

2020-02-20

Abstract excerpt

<h4>Importance</h4> New drugs which provide benefit alongside statin mono-therapy are warranted to reduce risk of cardiovascular disease. <h4>Objective</h4> To systematically evaluate the genetically predicted effects of 8,851 genes and cardiovascular disease risk factors using data from the UK Biobank and subsequently prioritize their potential to reduce cardiovascular disease in addition to statin therapy. <h4>D...

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Literature Corpus work: 19566ce1-7ea3-5d26-a395-dc379a17a168
DOI: 10.1101/2020.02.16.20023010

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