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Article

Blood Pressure and Risk of Cardiovascular Disease in UK Biobank: A Mendelian Randomization Study.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2021

Wan Eric Yuk Fai, Fung Wing Tung, Schooling C Mary, Au Yeung Shiu Lun, Kwok Man Ki, Yu Esther Yee Tak, Wang Yuan, Chan Esther Wai Yin, Wong Ian Chi Kei, Lam Cindy Lo Kuen

Abstract excerpt

This study aims to evaluate the causal association of blood pressure (BP) with cardiovascular diseases (CVDs). Two-sample Mendelian randomization was performed using a large genome-wide association study (n=299 024) and the UK Biobank cohort (n=375 256). We identified 327 and 364 single-nucleotide polymorphisms strongly and independently associated with systolic BP and diastolic BP, respectively, as genetic...

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Identifiers

PMID: 33390054
DOI: 10.1161/HYPERTENSIONAHA.120.16138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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