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Placenta <i>hIGF1</i> nanoparticle treatment in guinea pigs mitigates fetal sex dependent FGR-associated effects on kidney structure and blood pressure-related signaling pathways

2025-03-13

Abstract excerpt

<h4>ABSTRACT</h4> Fetal development in an adverse in utero environment significantly increases the risk of hypertension and cardiovascular disease. The kidneys play a pivotal role in the regulation of blood pressure and cardiovascular function, and perturbations in kidney structure and molecular profile are often demonstrated in offspring born fetal growth restricted (FGR). The aim of this study was to determine...

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Literature Corpus work
194a0bf5-d3df-5815-8ed1-b430e112ee34
DOI
10.1101/2025.03.10.642360
Open publication

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