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Article

Maternal-fetal interfaces transcriptome changes associated with placental insufficiency and a novel gene therapy intervention

2024-06-08

Abstract excerpt

The etiology of fetal growth restriction (FGR) is multifactorial, although many cases often involve placental insufficiency. Placental insufficiency is associated with inadequate trophoblast invasion resulting in high resistance to blood flow, decreased availability of nutrients, and increased hypoxia. We have developed a non-viral, polymer-based nanoparticle that facilitates delivery and transient gene expression...

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Literature Corpus work
57f412fc-de1f-5e27-a4d0-74aa3435cbfc
DOI
10.1101/2024.06.05.597595
Open publication

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Maternal-fetal interfaces transcriptome changes associated with placental insufficiency and a novel gene therapy interventionDOI 10.1101/2024.06.05.597595
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