Article
Mid-pregnancy placental transcriptome in a model of placental insufficiency with and without novel intervention
2024-06-09
Abstract excerpt
Fetal growth restriction (FGR) affects between 5-10% of all live births. Placental insufficiency is a leading cause of FGR, resulting in reduced nutrient and oxygen delivery to the fetus. Currently, there are no effective in utero treatment options for FGR, or placental insufficiency. We have developed a gene therapy to deliver, via a non-viral nanoparticle, human insulin-like 1 growth factor ( hIGF1 ) to the pl...
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Identifiers and source
- Literature Corpus work
- 64acfaa1-2d2d-53b6-8577-dfc102fb1232
- DOI
- 10.1101/2024.06.05.597621
