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Placental Nanoparticle-mediated IGF1 Gene Therapy Corrects Fetal Growth Restriction in a Guinea Pig Model

2024-04-10

Abstract excerpt

<h4>ABSTRACT</h4> Fetal growth restriction (FGR) caused by placental insufficiency is a major contributor to neonatal morbidity and mortality. There is currently no in utero treatment for placental insufficiency or FGR. The placenta serves as the vital communication, supply, exchange, and defense organ for the developing fetus and offers an excellent opportunity for therapeutic interventions. Here we show efficac...

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Literature Corpus work
e853c6d7-0fac-5194-a268-a622b2ed5593
DOI
10.1101/2024.04.05.587765
Open publication

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Placental Nanoparticle-mediated IGF1 Gene Therapy Corrects Fetal Growth Restriction in a Guinea Pig ModelDOI 10.1101/2024.04.05.587765
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