Article

Postsynaptic serine racemase regulates NMDA receptor function

2020-06-16

Abstract excerpt

D-serine is the primary NMDA receptor (NMDAR) co-agonist at mature forebrain synapses and is synthesized by the enzyme serine racemase (SR). However, our understanding of the mechanisms regulating the availability of synaptic D-serine remains limited. Though early studies suggested D-serine is synthesized and released from astrocytes, more recent studies have demonstrated a predominantly neuronal localization of S...

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Literature Corpus work: 18535adc-fda5-574a-9fb4-ebd150076cc9
DOI: 10.1101/2020.06.16.155572

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