Article
Zili is required for germ cell differentiation and meiosis in zebrafish.
The EMBO journal - 22 Oct 2008
Houwing Saskia, Berezikov Eugene, Ketting René F
Abstract excerpt
Small RNAs exert an effect through diverse RNA interference pathways to transcriptionally or post-transcriptionally silence their targets. The Piwi-interacting RNAs (piRNAs) represent a germline-specific small RNA pathway where Piwi proteins themselves are thought to mediate piRNA biosynthesis. Here, we provide strong evidence for a piRNA amplification loop in zebrafish, in which Ziwi and Zili bind piRNAs of...
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