pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.

doi:10.1091/mbc.12.11.3476

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Article

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.

Molecular biology of the cell - 1 Nov 2001

Troxell C L, Sweezy M A, West R R, Reed K D, Carson B D, Pidoux A L, Cande W Z, McIntosh J R

Abstract excerpt

We have identified Klp2p, a new kinesin-like protein (KLP) of the KAR3 subfamily in fission yeast. The motor domain of this protein is 61% identical and 71% similar to Pkl1p, another fission yeast KAR3 protein, yet the two enzymes are different in behavior and function. Pkl1p is nuclear throughout the cell cycle, whereas Klp2p is cytoplasmic during interphase. During mitosis Klp2p enters the nucleus where it...

Topics

Alleles
Amino Acid Sequence
Cell Cycle Proteins
Dyneins
Fungal Proteins
Genes, Fungal
Kinesins
Meiosis
Membrane Proteins
Microtubule-Associated Proteins
Mitosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nuclear Proteins

Phosphoproteins

Saccharomyces cerevisiae Proteins

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Homology, Amino Acid

Source

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Identifiers

PMID: 11694582
DOI: 10.1091/mbc.12.11.3476
PMCID: PMC60269

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