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Article

Re-appraising the role of T-cell derived interferon gamma in restriction of <i>Mycobacterium tuberculosis</i> in the murine lung

2024-04-05

Abstract excerpt

<h4>ABSTRACT</h4> T cells producing interferon gamma (IFNγ) have long been considered a stalwart for immune protection against Mycobacterium tuberculosis ( Mtb ), but their relative importance to pulmonary immunity has been challenged by murine studies which achieved protection by adoptively transferred Mtb -specific IFNγ -/- T cells. Using IFNγ -/- T cell chimeric mice and adoptive transfer of IFNγ -/- T c...

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Literature Corpus work
1727fde9-fbde-52ef-877d-98ae102feefa
DOI
10.1101/2024.04.04.588086
Open publication

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Re-appraising the role of T-cell derived interferon gamma in restriction of <i>Mycobacterium tuberculosis</i> in the murine lungDOI 10.1101/2024.04.04.588086
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