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Exposure to <i>mycobacterium</i> remodels alveolar macrophages and the early innate response to <i>Mycobacterium tuberculosis</i> infection

2022-09-19

Abstract excerpt

Alveolar macrophages (AMs) play a critical role during Mycobacterium tuberculosis (Mtb) infection as the first cells in the lung to encounter bacteria. We previously showed that AMs initially respond to Mtb in vivo by mounting a cell-protective, rather than pro-inflammatory response. However, the plasticity of the initial AM response was unknown. Here, we characterize how previous exposure to mycobacterium , ei...

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Identifiers and source

Literature Corpus work
8e38ce2c-ca25-5667-aff0-e68d5d3fb264
DOI
10.1101/2022.09.19.507309
Open publication

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Exposure to <i>mycobacterium</i> remodels alveolar macrophages and the early innate response to <i>Mycobacterium tuberculosis</i> infectionDOI 10.1101/2022.09.19.507309
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