Article

HDAC6 inhibition to treat heart failure with preserved ejection fraction

2023-06-16

Abstract excerpt

Heart failure with preserved ejection fraction (HFpEF) is a prevalent health condition associated with high morbidity and mortality, but currently, there are few effective therapies. Our previous research showed that inhibiting histone deacetylase 6 (HDAC6) had a beneficial effect on a genetic cardiomyopathy model. The overlapping underlying mechanisms involving inflammation and metabolism between cardiomyopathy a...

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Literature Corpus work: 16587087-e6b6-5a6f-8e83-dc9b8b5121e5
DOI: 10.21203/rs.3.rs-2997460/v1

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