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Histone lysine demethylase inhibition is a disease-modifying therapy for hypertrophic cardiomyopathy

2026-08-13

Abstract excerpt

Rationale: Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disorder characterized by cardiac hypertrophy, fibrosis, arrhythmias, and sudden cardiac death (SCD). Although current therapies primarily target sarcomere dysfunction, the contribution of epigenetic dysregulation to HCM pathogenesis and its therapeutic potential remain poorly understood. <h4>Objective:</h4> To determine whether pharmacolog...

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Literature Corpus work
1b531433-3d8b-5b2b-b9c6-3b7839cee96a
DOI
10.64898/2026.08.07.743611
Open publication

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Histone lysine demethylase inhibition is a disease-modifying therapy for hypertrophic cardiomyopathyDOI 10.64898/2026.08.07.743611
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