Article

RNAs anchoring replication complex control initiation and firing of DNA replication

2025-01-28

Abstract excerpt

<title>Abstract</title> <p>Coordinated initiation of DNA replication is essential to ensure efficient and timely DNA synthesis. Yet, molecular mechanism describing how replication initiation is coordinated in eukar-yotic cells is not completely understood. Herein, we present data demonstrating a novel feature of RNAs transcribed in the proximity of actively replicating gene loci. We show that RNAs aN-Choring ORC1...

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Literature Corpus work: 16062a32-678f-5e7e-851f-aa933bd808e7
DOI: 10.21203/rs.3.rs-5723221/v1

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