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Zebrafish Cre/ <i>lox</i> regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivation

2021-06-18

Abstract excerpt

The ability to regulate gene activity spatially and temporally is essential to investigate cell type specific gene function during development and in postembryonic processes and disease models. The Cre/ lox system has been widely used for performing cell and tissue-specific conditional analysis of gene function in zebrafish, but simple and efficient methods for isolation of stable, Cre/ lox regulated alleles are...

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Literature Corpus work
15daab28-440c-5ae4-b840-b8df97757308
DOI
10.1101/2021.06.18.448732
Open publication

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Zebrafish Cre/ <i>lox</i> regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivationDOI 10.1101/2021.06.18.448732
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