Article

Cre-Lox miRNA-delivery technology optimized for inducible microRNA and gene-silencing studies in zebrafish

2024-02-23

Abstract excerpt

<h4>ABSTRACT</h4> While many genetic tools exist for zebrafish, this animal model is still lacking a robust gene-silencing and microRNA-delivery technology enabling spatio-temporal control and reliable traceability. We have recently demonstrated that the use of engineered pri-miR backbones can be used to both trigger stable and heritable gene knockdown and/or express microRNA(s) of choice in this organism. This a...

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Literature Corpus work: 4ad2928d-0d98-5e6c-b22a-78b3e7760d46
DOI: 10.1101/2024.02.22.581357

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