Article
A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants.
Scientific reports - 4 Sept 2017
Ma Zhipeng, Zhu Peipei, Pang Meijun, Guo Liwei, Chang Nannan, Zheng Jiyuan, Zhu Xiaojun, Gao Ce, Huang Honghui, Cui Zongbin, Xiong Jing-Wei, Peng Jinrong, Chen Jun
Abstract excerpt
Conventional genetic screens for recessive mutants are inadequate for studying biological processes in the adult vertebrate due to embryonic lethality. Here, we report that a novel inducible mutagenesis system enables to study gene function in both embryonic and adult zebrafish. This system yield...
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