Article

A stromal-state dichotomy governs recalcitrance or remission in inflammatory bowel disease

2026-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Inflammatory bowel diseases (IBD) remain a relapsing, treatment-refractory disorder marked by progressive tissue injury and inflammation despite expanding immune-targeted therapies. We established a prospective cohort integrating stromal biobanking, functional phenotyping, cross-cohort benchmarking, and outcome modeling to define disease-anchored cellular states. Colonic myofibroblasts from 34 i...

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Literature Corpus work: 15d970ba-ab1b-5e47-ae95-6fb2a024b4c5
DOI: 10.64898/2026.05.01.720931

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