Article

Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution

2025-05-11

Abstract excerpt

<h4>ABSTRACT</h4> The intestinal epithelium is often a site of pathology, such as in inflammatory bowel disease (IBD), and its maintenance is highly modulated by interactions with the microenvironment. However, a systematic understanding of how the myriad of niche cues impact distinct epithelial cell types in a diseased context is still lacking. To address this gap, we first benchmarked diverse human colonic orga...

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Literature Corpus work: d974f86f-a541-5da6-8074-190b153eaa4a
DOI: 10.1101/2025.05.06.652311

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