Article

Intestinal Stem and Progenitor Cells Exhibit Distinct Adaptive Responses to Inflammatory Stress in IBD

2025-12-13

Abstract excerpt

<h4>Background</h4> Intestinal epithelial stem cells (SCs) and their transit-amplifying (TA) progeny are critical for mucosal repair and regeneration. However, their behaviour under chronic inflammatory conditions, such as those observed in Inflammatory Bowel Disease (IBD), remains incompletely understood. <h4>Methods</h4> We investigated the impact of chronic inflammation on intestinal stem/progenitor cells by...

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Literature Corpus work: 17d7edea-aebf-5981-8917-5addba969566
DOI: 10.64898/2025.12.11.691866

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