Article

Single-cell analysis of an adult IBD INCEPTION cohort reveals Galectin-linked disease mechanisms

2026-07-03

Abstract excerpt

<h4>Background and Aims</h4> The molecular pathogenesis of Inflammatory Bowel Disease (IBD) remains unclear. We aimed to establish a high-resolution immune landscape of treatment-naïve IBD to identify central drivers of disease onset and early pathogenic signalling. <h4>Methods</h4> We generated a single-cell atlas using intestinal biopsies from a large adult inception cohort of 137 individuals, including treatm...

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Literature Corpus work: 6dcb2359-6fb1-59ac-9068-09466371fd71
DOI: 10.64898/2026.06.30.735473

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