Article

A Living Organoid Biobank of Crohn’s Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics

2023-03-13

Abstract excerpt

<h4>ABSTRACT (Structured)</h4> Crohn’s disease (CD) is a complex, clinically heterogeneous disease of multifactorial origin; there is no perfect pre-clinical model, little insight into the basis for such heterogeneity, and still no cure. To address these unmet needs, we sought to explore the translational potential of adult stem cell-derived organoids that not only retain their tissue identity, but also their gen...

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Literature Corpus work: 2770f1a5-69a9-59ec-a393-9c0dcee88483
DOI: 10.1101/2023.03.11.532245

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