Article

Epithelia mediate inflammation with myeloid cells in Crohn’s disease patients under treatment

2025-03-31

Abstract excerpt

<h4>SUMMARY</h4> Crohn’s disease (CD), a major class of Inflammatory Bowel Disease (IBD), is a chronic condition affecting millions, with >50% of the patients experiencing relapses marked by inflammation. Our cellular atlas (380,000 cells) of the terminal ileum (TI) and ascending colon (AC) mucosa from 46 CD and non-IBD donors across various clinical condition, decipher disease heterogeneity for CD relapse and re...

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Literature Corpus work: 6e6082dc-06a5-551c-9fe6-38e0e570be32
DOI: 10.1101/2025.03.26.645552

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