Article

Somatic mutation but not aneuploidy differentiates lung cancer in never-smokers and smokers

2023-01-06

Abstract excerpt

<h4>Summary</h4> Lung cancer in never-smokers disproportionately affects older women. To understand the mutational landscape of this cohort, we performed detailed genome characterization of 73 lung adenocarcinomas from participants of the Women’s Health Initiative (WHI). We find enrichment of EGFR mutations in never-/light-smokers and KRAS mutations in heavy smokers as expected, but we also show that the specif...

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Literature Corpus work: 15ba4f08-783f-5c5e-a57b-bd08fbc1cadf
DOI: 10.1101/2023.01.05.522947

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