Article
The genomic landscape of lung cancer in never-smokers from the Women's Health Initiative.
JCI insight - 25 Jul 2024
Moorthi Sitapriya, Paguirigan Amy, Itagi Pushpa, Ko Minjeong, Pettinger Mary, Hoge Anna Ch, Nag Anwesha, Patel Neil A, Wu Feinan, Sather Cassie, Levine Kevin M, Fitzgibbon Matthew P, Thorner Aaron R, Anderson Garnet L, Ha Gavin, Berger Alice H
Abstract excerpt
Over 200,000 individuals are diagnosed with lung cancer in the United States every year, with a growing proportion of cases, especially lung adenocarcinoma, occurring in individuals who have never smoked. Women over the age of 50 comprise the largest affected demographic. To understand the genomic drivers of lung adenocarcinoma and therapeutic response in this population, we performed whole genome and/or whole...
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