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Article

SNV identification from single-cell RNA sequencing data.

Human molecular genetics - 1 Nov 2019

Schnepp Patricia M, Chen Mengjie, Keller Evan T, Zhou Xiang

Abstract excerpt

Integrating single-cell RNA sequencing (scRNA-seq) data with genotypes obtained from DNA sequencing studies facilitates the detection of functional genetic variants underlying cell type-specific gene expression variation. Unfortunately, most existing scRNA-seq studies do not come with DNA sequencing data; thus, being able to call single nucleotide variants (SNVs) from scRNA-seq data alone can provide crucial and...

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Share to Databases, Genetic
Share to Genetic Variation
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Single-Cell Analysis

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Identifiers

PMID: 31504520
DOI: 10.1093/hmg/ddz207
PMCID: PMC7279618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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