Article

SCANBIT facilitates identification of tumor cell populations in scRNAseq data using pseudobulked SNV calls

2026-01-28

Abstract excerpt

<h4>Motivation</h4> Single cell RNAseq (scRNAseq) is an ideal tool to characterize the heterogeneity within the tumor microenvironment, however, accurate identification of tumor cells can be a challenge. Reference-based methods can be inaccurate, if reference datasets are even available. Current purpose-built methods can be inaccurate, particularly with highly heterogeneous tumor types. Improved methods are neede...

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Literature Corpus work: a63d3762-6729-54c5-adb2-8e05e91a1e26
DOI: 10.64898/2026.01.27.701834

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