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Article

Single-cell sequencing to quantify genomic integrity in cancer.

The international journal of biochemistry & cell biology - 1 Jan 2018

van den Bos Hilda, Bakker Bjorn, Spierings Diana C J, Lansdorp Peter M, Foijer Floris

Abstract excerpt

The use of single-cell DNA sequencing (sc-seq) techniques for the diagnosis, prognosis and treatment of cancer is a rapidly developing field. Sc-seq research is gaining momentum by decreased sequencing costs and continuous improvements in techniques. In this review, we provide an overview of recent advancements in the field of sc-seq in cancer and we discuss how sc-seq can contribute to improved care for cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28951245
DOI: 10.1016/j.biocel.2017.09.016

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