Article

Exploiting Family History in Aggregation Unit-based Genetic Association Tests

2021-04-06

Abstract excerpt

The development of sequencing technology calls for new powerful methods to detect disease associations and lower the cost of sequencing studies. Family history (FH) contains information on disease status of relatives, adding valuable information about the probands’ health problems and risk of diseases. Incorporating data from FH is a cost-effective way to improve statistical evidence in genetic studies, and moreov...

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Literature Corpus work: 3cf6bd33-cfa8-5e17-af83-754b56969581
DOI: 10.1101/2021.04.05.438533

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