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An integrated view of the structure and function of the human 4D nucleome

2024-09-19

Abstract excerpt

The dynamic three-dimensional (3D) organization of the human genome (the “4D Nucleome”) is closely linked to genome function. Here, we integrate a wide variety of genomic data generated by the 4D Nucleome Project to provide a detailed view of human 3D genome organization in widely used embryonic stem cells (H1-hESCs) and immortalized fibroblasts (HFFc6). We provide extensive benchmarking of 3D genome mapping assay...

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Literature Corpus work
26a9668f-c501-56bc-9024-0e6130ef95bd
DOI
10.1101/2024.09.17.613111
Open publication

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An integrated view of the structure and function of the human 4D nucleomeDOI 10.1101/2024.09.17.613111
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