Article

Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells

2024-04-22

Abstract excerpt

Comprehensive analysis of chromatin architecture is crucial for understanding the gene regulatory programs during development and in disease pathogenesis, yet current methods often inadequately address the unique challenges presented by analysis of heterogeneous tissue samples. Here, we introduce Droplet Hi-C, which employs a commercial microfluidic device for high-throughput, single-cell chromatin conformation pr...

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Literature Corpus work: 8915b663-5e18-5bae-9a9a-e159b328377e
DOI: 10.1101/2024.04.18.590148

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