Article

Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing

2022-11-08

Abstract excerpt

<h4>ABSTRACT</h4> Mosaic mutations in blood are common with increasing age and are prognostic markers for cancer, cardiovascular dysfunction and other diseases. This group of acquired mutations include megabase-scale mosaic chromosomal alterations (mCAs). These large mutations have mainly been surveyed using SNP array data from individuals of European (EA) or Japanese genetic ancestry. To gain a better understand...

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Literature Corpus work: 13cea884-0eef-56c3-9844-ca4a8ba2eaec
DOI: 10.1101/2022.11.07.515222

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