Article

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

2020-11-16

Abstract excerpt

<title>Abstract</title> <p>Age is the dominant risk factor for infectious diseases, but the mechanisms linking the two are incompletely understood1,2. Age-related mosaic chromosomal alterations (mCAs) detected from blood-derived DNA genotyping, are structural somatic variants associated with aberrant leukocyte cell counts, hematological malignancy, and mortality3-11. Whether mCAs represent independent risk factor...

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Literature Corpus work: af9a0b0a-f39f-51e3-b979-d3f9a7b6fea6
DOI: 10.21203/rs.3.rs-100817/v1

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