Article

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

2020-11-16

Abstract excerpt

<h4>Summary Paragraph</h4> Age is the dominant risk factor for infectious diseases, but the mechanisms linking the two are incompletely understood 1,2 . Age-related mosaic chromosomal alterations (mCAs) detected from blood-derived DNA genotyping, are structural somatic variants associated with aberrant leukocyte cell counts, hematological malignancy, and mortality 3-11 . Whether mCAs represent independent risk fac...

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Literature Corpus work: 7309c315-b11f-558e-9c6a-67223741ed65
DOI: 10.1101/2020.11.12.20230821

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