Article

Geography, Ancestry, Age and Sex Shape Somatic Autosomal Mosaic Chromosomal Alterations in Blood

2025-10-20

Abstract excerpt

<h4>Summary</h4> Clonal hematopoiesis, through the age-associated accumulation of somatic mutations in blood, is strongly associated with hematological malignancies and other chronic diseases. These mutations have largely been characterized in individuals of European ancestry or environments, and consequently, it remains unclear how mutation-recurrence patterns vary across populations of different histories or no...

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Literature Corpus work: 11280a63-3788-5b5a-87e7-03f6738ead4c
DOI: 10.1101/2025.10.19.25338239

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