Article

Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood

2024-04-19

Abstract excerpt

Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in human blood. The presence of mLOY is associated with altered blood cell counts and increased risk of Alzheimer’s disease, solid tumors, and other age-related diseases. We sought to gain a better understanding of genetic drivers and associated phenotypes of mLOY through analyses of whole genome sequencing of a large set of genetic...

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Literature Corpus work: 16d0f1c7-b67e-5396-a2c9-9faf8745a3cd
DOI: 10.1101/2024.04.16.24305851

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