Article

The link between mRNA 3' tagging and nonsense-mediated mRNA decay (NMD) in Aspergillus nidulans

2018-01-01

Abstract excerpt

The focus of this study was to characterise the nonsense-mediated mRNA decay (NMD) complex and its link to mRNA 3' tagging in Aspergillus nidulans. The human histone H2a and H3 encoding transcripts were the first mRNAs reported to be oligouridylated. This was shown to involve Upf1, which is recruited by the stem-loop binding protein (SLBP) in response to DNA synthesis being blocked; Upf1 recruitment promotes 3' ta...

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Literature Corpus work: 13be5e33-7655-5158-af53-63c524b8bb36
DOI: 10.17638/03034476

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