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Article

mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation.

Molecular and cellular biology - 1 Jul 2012

Morozov Igor Y, Jones Meriel G, Gould Peter D, Crome Victoria, Wilson James B, Hall Anthony J W, Rigden Daniel J, Caddick Mark X

Abstract excerpt

For a range of eukaryote transcripts, the initiation of degradation is coincident with the addition of a short pyrimidine tag at the 3' end. Previously, cytoplasmic mRNA tagging has been observed for human and fungal transcripts. We now report that Arabidopsis thaliana mRNA is subject to 3' tagging with U and C nucleotides, as in Aspergillus nidulans. Mutations that disrupt tagging, including A. nidulans cutA and...

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Identifiers

PMID: 22547684
DOI: 10.1128/MCB.00316-12
PMCID: PMC3434495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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