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Article

Transcription termination and nuclear degradation of cryptic unstable transcripts: a role for the nrd1-nab3 pathway in genome surveillance.

Molecular cell - 15 Sept 2006

Thiebaut Marilyne, Kisseleva-Romanova Elena, Rougemaille Mathieu, Boulay Jocelyne, Libri Domenico

Abstract excerpt

Cryptic unstable transcripts (CUTs) are widely distributed in the genome of S. cerevisiae. These RNAs generally derive from nonannotated regions of the genome and are degraded rapidly and efficiently by the nuclear exosome via a pathway that involves degradative polyadenylation by a new poly(A) polymerase borne by the TRAMP complex. What is the share of significant information that is encrypted in CUTs and what...

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Identifiers

PMID: 16973437
DOI: 10.1016/j.molcel.2006.07.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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