Article

AtacWorks: A deep convolutional neural network toolkit for epigenomics

2019-11-04

Abstract excerpt

We introduce AtacWorks ( https://github.com/clara-genomics/AtacWorks ), a method to denoise and identify accessible chromatin regions from low-coverage or low-quality ATAC-seq data. AtacWorks uses a deep neural network to learn a mapping between noisy ATAC-seq data and corresponding higher-coverage or higher-quality data. To demonstrate the utility of AtacWorks, we train a model on data from four human blood cell...

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Literature Corpus work: af67d783-ac52-523c-a390-8dae642a882a
DOI: 10.1101/829481

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