Article

Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism

2023-09-22

Abstract excerpt

Duplication 15q (dup15q) syndrome is the most common genetic cause of autism spectrum disorder (ASD). Due to a higher genetic and phenotypic homogeneity compared to idiopathic autism, dup15q syndrome provides a well-defined setting to investigate ASD mechanisms. Previous bulk gene expression studies identified shared molecular changes in ASD. However, how cell type specific changes compare across different autism...

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Literature Corpus work: 12641a8d-b896-58c1-afc5-addaf5345a44
DOI: 10.1101/2023.09.22.559056

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