Article

Spatiotemporal analysis of autism gene enrichment implicates cortex, thalamus, and hypothalamus

2026-05-14

Abstract excerpt

Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental disorder. Sequencing analyses have identified 185 ASD-associated genes, which implicate neurons, but the specific brain regions through which these neurons influence neurodevelopment remain unclear. Here, we integrate over one million single-cell RNA sequencing profiles from 20 regions of the developing human brain (4–23 post-conceptual weeks)...

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Literature Corpus work: 7ba66d38-88f7-5c32-8bdf-d934a8ad9fd4
DOI: 10.64898/2026.05.14.724487

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