Article

Single cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss of function mutation genes regulating glial cells

2021-08-09

Abstract excerpt

<h4>Background: </h4> In recent years, several hundred autism spectrum disorder (ASD) implicated genes have been discovered impacting a wide range of molecular pathways. However, the molecular underpinning of ASD, particularly from the point of view of ‘brain to behaviour’ pathogenic mechanisms, remains largely unknown. Methods We undertook a study to investigate patterns of spatiotemporal and cell type expressio...

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Literature Corpus work: f7b29eb7-fab7-5bd3-987f-9e435d1fa9df
DOI: 10.21203/rs.3.rs-763046/v1

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