Article

Global changes in patterning, splicing and primate specific lncRNAs in autism brain

2016-09-23

Abstract excerpt

<h4>Summary</h4> We apply transcriptome-wide RNA sequencing in postmortem autism spectrum disorder (ASD) brain and controls and identify convergent alterations in the noncoding transcriptome, including primate specific lncRNA, and transcript splicing in ASD cerebral cortex, but not cerebellum. We characterize an attenuation of patterning between frontal and temporal cortex in ASD and identify SOX5 , a transcript...

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Literature Corpus work: d76f5b3e-e4b6-537d-8bab-618cff5684e5
DOI: 10.1101/077057

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