Convergent Sequence Features of Antiviral B Cells

Abstract excerpt

<h4>SUMMARY</h4> Throughout life, humans experience repeated exposure to viral antigens through infection and vaccination, building diverse antigen-specific antibody repertoires. In recent years, these repertoires have become an important source for novel antibody-based antiviral therapeutics, yet there is still limited understanding of the determinants of antibody-antigen specificity. Here, we generated a large...

Topics

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• Antibodies, Viral
• Antigens, Viral
• COVID-19
• COVID-19 Vaccines
• Cytomegalovirus and herpesvirus research
• Immune Cell Function and Interaction
• Receptors, Antigen, B-Cell
• T-cell and B-cell Immunology

Identifiers and source

Literature Corpus work

20a4b3f8-81ef-5731-852f-f8a65e3b0aba

DOI

10.1101/2023.09.06.556442