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Article

High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site.

Science translational medicine - 11 Jul 2012

Sundling Christopher, Li Yuxing, Huynh Nick, Poulsen Christian, Wilson Richard, O'Dell Sijy, Feng Yu, Mascola John R, Wyatt Richard T, Karlsson Hedestam Gunilla B

Abstract excerpt

The high overall genetic homology between humans and rhesus macaques, coupled with the phenotypic conservation of lymphocyte populations, highlights the potential use of nonhuman primates (NHPs) for the preclinical evaluation of vaccine candidates. For HIV-1, experimental models are needed to identify vaccine regimens capable of eliciting desired immune responses, such as broadly neutralizing antibodies (bNAbs)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22786681
DOI: 10.1126/scitranslmed.3003752
PMCID: PMC5378478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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