Article

H2A.B is a cancer/testis factor involved in activation of ribosome biogenesis in Hodgkin Lymphoma

2021-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Testis-specific regulators of chromatin function are commonly ectopically expressed in human cancers, but their roles are poorly understood. Examination of 81 primary Hodgkin Lymphoma (HL) samples showed that the ectopic expression of the eutherian testis-specific histone variant H2A.B is an inherent feature of HL. In experiments using two HL-derived cell lines derived from different subtypes of...

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Literature Corpus work: 10e8d872-979e-5e4c-8401-259319ed4522
DOI: 10.1101/2021.01.19.427265

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