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Article

H2A.B facilitates transcription elongation at methylated CpG loci.

Genome research - 1 Apr 2014

Chen Yibin, Chen Qiang, McEachin Richard C, Cavalcoli James D, Yu Xiaochun

Abstract excerpt

H2A.B is a unique histone H2A variant that only exists in mammals. Here we found that H2A.B is ubiquitously expressed in major organs. Genome-wide analysis of H2A.B in mouse ES cells shows that H2A.B is associated with methylated DNA in gene body regions. Moreover, H2A.B-enriched gene loci are actively transcribed. One typical example is that H2A.B is enriched in a set of differentially methylated regions at...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24402521
DOI: 10.1101/gr.156877.113
PMCID: PMC3975057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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