Article

Novel classes and evolutionary turnover of histone H2B variants in the mammalian germline

2021-09-05

Abstract excerpt

Histones and their post-translational modifications facilitate diverse chromatin functions in eukaryotes. Core histones (H2A, H2B, H3, and H4) package genomes after DNA replication. In contrast, variant histones promote specialized chromatin functions, including DNA repair, genome stability, and epigenetic inheritance. Previous studies have identified only a few H2B variants in animals; their roles and evolutionar...

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Literature Corpus work: f0a2f879-d81b-58e7-86ae-1d2c187e0776
DOI: 10.1101/2021.09.05.459003

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