Article
The histone variant H2A.Bbd is enriched at sites of DNA synthesis.
Nucleic acids research - 1 Jun 2014
Sansoni Viola, Casas-Delucchi Corella S, Rajan Malini, Schmidt Andreas, Bönisch Clemens, Thomae Andreas W, Staege Martin S, Hake Sandra B, Cardoso M Cristina, Imhof Axel
Abstract excerpt
Histone variants play an important role in shaping the mammalian epigenome and their aberrant expression is frequently observed in several types of cancer. However, the mechanisms that mediate their function and the composition of the variant-containing chromatin are still largely unknown. A proteomic interrogation of chromatin containing the different H2A variants macroH2A.1.2, H2A.Bbd and H2A revealed a...
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